Syntheses of functionalized polymethacrylamides based on methionine oxides

Abstract Radical polymerizations of methacrylamides having methionine, methionine sulfoxide, and methionine sulfone moieties, and oxidations of the polymethacrylamide having a methionine moiety were examined. The radical polymerizations of the monomers were carried out using 2,2′-azobis(isobutyronitrile) (AIBN) as an initiator to afford the corresponding polymers in good yields. The polymer with a methionine structure was oxidized by 2 and 10 equivalents of hydrogen peroxide to obtain polymers having methionine sulfoxide and sulfone structures in the side chains, respectively.