Clinical characteristics of SF3B1 mutant (mut) uveal melanoma (UM) and response to immune checkpoint inhibition (ICI).

Joe M. Grimes,Alexander N. Shoushtari,Marlana Orloff,Shaheer Khan,Cody Chiuzan,Susan Jean Hsiao,Diana McDonnell,Brian P. Marr,Richard D. Carvajal

Clinical characteristics of SF3B1 mutant (mut) uveal melanoma (UM) and response to immune checkpoint inhibition (ICI).

2021

Joe M. Grimes
Alexander N. Shoushtari
Marlana Orloff
Shaheer Khan
Cody Chiuzan
Susan Jean Hsiao
Diana McDonnell
Brian P. Marr
Richard D. Carvajal

9535Background: Metastatic UM is associated with a median overall survival (OS) < 1 year (yr) and overall response rate (RR) to ICI < 18%. SF3B1 mut UM represent a clinically unique subset of UM, d...

Keywords:

Melanoma
Cancer research
overall survival
Medicine
Immune checkpoint
Mutant
overall response rate

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