Effects of dietary protein and butylated hydroxytoluene on the kidneys of rats

Summary Semipurified diet using Na-caseinate or lactalbumin as the only protein source was given to female rats to study the influence of nephrocalcinosis on butylated hydroxy toluene (BUT) induced kidney damage. The study showed, that BUT induces nephropathy in female rats irrespective of the diet used. Pronounced nephrocalcinosis was only found in rats fed the Nacaseinate diet. Thus, this study does not indicate a connection between the development of the BUT-nephropathy and nephrocalcinosis. The results from this study once more stress the influence of the diet on reaction of the animal to experimental procedures.