Analysis of macular thickness in British population using optical coherence tomography (OCT): an emphasis on interocular symmetry.

Purpose: To evaluate macular thickness measurements in normal subjects from British origin, to assess interocular asymmetry using optical coherence tomography (OCT) and to establish standard values for macular and foveal thickness. Methods: Two hundred eyes of 100 normal individuals underwent serial scans using fast macular thickness map protocol in the Stratus OCT version 3.51, with foveal fixation. Minimum foveal thickness (MFT), central 1 mm average foveal thickness (AFT), total foveal volume (TFV) and total macular volume (TMV at 6 mm) of both eyes were assessed. The interocular asymmetry was measured and statistically analyzed. Results: The mean ± SD (N = 200) was 173 ± 23 μm for MFT and 203 ± 24 μm for AFT. The mean difference ± SD between the two eyes was (3.5 ± 14.5 μm at p = 0.17) for MFT, (6.4 ± 14.7 μm at p = 0.06) for AFT, (0.007 mm3 ± 0.007 at p = 0.06) for TFV and (0.19 ± 0.35 at p = 0.07) for TMV. Conclusion: Our study provides a normative database for macular thickness and volume parameter...