The dependence of raman scattering on the conformation of ribosomal RNA

Summary The intensities of Raman scattering from certain vibrations of nucleotide residues in 16S and 23S ribosomal RNA are sensitive to changes of RNA conformation with temperature. The intensity effects differ from those exhibited by polynucleotides and may be due to a specific RNA tertiary structure or to a sequence dependence of the Raman hypochromic effect.