A 10-year comparison of mitral valve replacement with Carpentier-Edwards and Hancock porcine bioprostheses

Abstract Two hundred fifty-three patients who underwent isolated mitral valve replacement with a porcine bioprosthesis had long-term evaluation. One hundred forty-seven patients received a Carpentier-Edwards porcine bioprosthesis and 106, a Hancock valve. There were no significant differences in preoperative clinical characteristics between the two groups. Cumulative follow-up was 1,375 patient-years. At 10 years, 93% ± 2.5% of the patients in the Carpentier-Edwards group and 85% ± 7.8% of those in the Hancock group were free from valve-related death (not significant), and 95% ± 2% and 91% ± 3.8%, respectively, were free ton thromboembolism (not significant). At 10 years, 65% ± 7.2% of the patients in the Carpentier-Edwards group and 66% ± 7.2% of those in the Hancock group were free from structural valve deterioration (not significant), and 64% ± 6% and 59% ± 7.3%, respectively, were free from reoperation (not significant). We conclude that the first generation of Carpentier-Edwards and Hancock prostheses produce comparable long-term results in the mitral position.