DORZOLAMIDE THERAPY IN X-LINKED RETINOSCHISIS AS EVALUATED BY SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY.

A 23 year old adolescent presented with diminished vision in both eyes since childhood. Examination revealed best corrected visual acuity of 20/200 with absent foveal reflex on indirect ophthalmoscopy. Further imaging with SD-OCT revealed schisis cavities in fovea and parafoveal region. A course of topical dozolamide was tried for a period of 8weeks, which showed improvement in terms of decrement in macular volume morphologically but this did not turn into functional visual gain. This case highlights role of SD-OCT in detecting subtle maculae pathologies and also in evaluating effectiveness of dozolamide therapy in improving visual potentials.