Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2.

To the editor: Recent large-scale sequencing studies report recurrent somatic mutations in the blood of elderly individuals in genes previously linked to clonal expansion of hematopoietic stem cells.[1][1][⇓][2][⇓][3]-[4][4] Particularly for DNMT3A and TET2 , a steep age-associated increase in