A Versatile and One-Pot Strategy to Synthesize α-Amino Ketones from Benzylic Secondary Alcohols Using N-Bromosuccinimide.
2015
A variety of α-amino ketones including some psychoactive drugs such as amfepramone (VIId) and pyrovalerone are efficiently obtained by a metal-free one-pot synthesis from readily available benzylic secondary alcohols and amines.
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