The diagnostic values of CT-guided transthoracic needle lung biopsy and transbronchoscopic lung biopsy for peripheral lung lesions

Objective To explore the values of CT-guided transthoracic needle lung biopsy ( TNLB ) and transbronchoscopic lung biopsy ( TBLB )in the clinical diagnosis by comparing the identification rates of both procedrues for peripheral lung lesions and the incidence rates of procedure-related complications.Methods 249 patients with peripheral lung lesions on radiographic examinations were divided into TNLB group( 153 patients ) and TBLB group ( 96 patients ) based on the method for lung biosy.The rate of lesion identification and the incidence rate of complications were compared between the two groups.Results The rate of lesion identification was markedly higher in TNLB group than in TBLB group ( 77.8％ vs.45.8％ ).The incidence of pneumothorax was similar in the two groups.The incidence of pulmonary hemorrhage was significantly higher in TBLB group than in TNLB group ( 53.1％ vs.7.2％ ),but the rate of bleeding volume of 30 ml or more did not differ significantly between the two groups.The incidence rates of tachycardia and decreased SaO2 were evidently higher in TBLB group than in TNLB group.Conlusions Both biopsies is a less invasive,safer procudure and have their own advantages and disadvantages.Combination of the two procedures is beneficial for the improvement of the identification rate of peripheral lung lesions. Key words: Peripheral lung lesions;  Transthoracic needle lung biopsy;  Transbronchoscopic lung biopsy