Synthese Aldosteron‐ähnlicher Corticosteroide. Racemisches 11‐Dehydroaldosteron (rac.‐18‐Oxo‐11‐dehydrocorticosteron) Über Steroide, 223. Mitteilung

Racemic 11-dehydroaldosterone (rac.-18-oxo-11-dehydrocorticosterone) is prepared starting from the 3, 3; 20, 20-bisethylene acetal of the racemic 3, 20-dioxo-11β, 21-dihydroxy-Δ-pregnene-18-oic acid-(18 11β)-lactone, an intermediate obtained previously in the first total synthesis of aldosterone. A cyclic 18(21)-hemiacetal structure is deduced for the new corticosteroid from spectroscopic and chemical evidence.