Abstract 20254: Left Atrial Dimensions Can Help in Predicting Thromboembolic Risk in Non Valvular Atrial Fibrillation Patients Treated With Direct Oral Anticoagulants

Introduction: The discriminative ability of the widely used CHA2DS2-VASc score for thromboembolic risk stratification in non valvular atrial fibrillation (NVAF) is known as modest, thus, it would be useful to have additional parameters to stratify it. Hypothesis: On the basis of pathophysiology of atrial thromboembolism, we assessed, in a real-world population of NVAF patients treated with direct oral anticoagulants (DOACs), the association between CHA2DS2-VASc, simple echocardiographic parameters such as left atrial antero-posterior diameter and left atrial volume and thromboembolic risk. Methods: We evaluated CHA2DS2-VASc score and following variables assessed with 2D transthoracic echocardiography: left atrial end-systolic antero-posterior diameter (LA diameter) and left atrial volume index (LAVI). We evaluated also 1-year incidence of ischemic stroke, TIA or arterial embolism. Statistical analysis was performed using simple linear regression and logistic regression. Results: Of 273 patients (129 treat...