Visible-light-promoted CN and CS bonds formation: A catalyst and solvent-free photochemical approach for the synthesis of 1,3-thiazolidin-4-ones

Abstract A visible-light-induced, one-pot mild and efficient, multicomponent-tandem synthesis of diversified 1,3-thiazolidin-4-ones under catalyst and solvent-free conditions is reported. Here, visible-light, an ideal source of energy, has been used as photochemical activator to generate C N and C S bonds under radical mechanistic pathway from aromatic amines, aldehydes and thioglycolic acid. The reported methodology can be extensively utilized to explore 1,3-thiazolidin-4-one derivatives with high selectivity, short reaction time, tolerance of functional groups, cost effectiveness and excellent yields.