Structures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family.

Ana Laura Stern,Agata Naworyta,Juan José Cazzulo,Sherry L. Mowbray

Structures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family.

2011

Ana Laura Stern
Agata Naworyta
Juan José Cazzulo
Sherry L. Mowbray

Ribose-5-phosphate isomerase (Rpi; EC 5.3.1.6) is a key activity of the pentose phosphate pathway. Two unrelated types of sequence/structure possess this activity: type A Rpi (present in most organ ...

Keywords:

Chagas disease
Molecular biology
Ribose-5-phosphate isomerase
Isomerase
Pentose phosphate pathway
Biochemistry
Trypanosoma cruzi
Biology
Sugar
Enzyme specificity

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