Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation
2017
O’Farrell et al. show that class III PI3K regulates epithelial integrity through endosomal LKB1. Class III PI3K inactivation dysregulates LKB1 to alter cell polarity, and the PtdIns3P effector WDFY2 regulates LKB1.
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