Distribution and drug resistance of pathogens causing urinary tract infections

OBJECTIVE To investigate the distribution and antimicrobial resistance of pathogens causing urinary tract infections,to provide reasonable reference for using antibiotics in clinic.METHODS The pathogens isolated from outpatients and inpatients with urinary tract infections between 2007 to 2009 were cultured,and bacterial identification and drug sensitivity test were performed by using automatic MicroScan 40/96 analyzer.RESULTS Among 369 strains of bacteria separated from the urinary tract,Gram-negative bacilli accounted for 81.03%,among which Escherichia coli was 56.91%,Klebsiella pneumoniae was 10.30%;Gram-positive cocci accounted for 14.09% and fungi accounted for 4.88%.The detection rates of ESBLs-producing E.coli and K.pneumoniae were 44.28% and 36.84%,respectively.The sensitive rate to imipenem of enterobacteriaceae was 100.00%,and the sensitive rates to vancomycin of staphylococcus,Enterococcus faecalis,and Enterococcus faecium were 100.00%.CONCLUSION E.coli is the main strain causing urinary tract infection,the multi-drug resistance is serious,In order to reduce the drug resistance,antibiotics should be reasonably used based on the results of drug sensitivity test.