Characteristics of critically ill patients infected with COVID-19 in Abu Dhabi, United Arab Emirates

This study's primary objective was to describe the clinical characteristics of patients with laboratory-confirmed COVID-19 admitted to the ICU at Cleveland Clinic Abu Dhabi On admission to ICU, lymphocytopenia was common (73%) Ferritin, C-reactive protein, and interleukin-6 were all elevated The median initial PaO2/FiO2 ratio was 82 [64-128] mmHg and improved on day 3 Forty patients (73%) required mechanical ventilation (MV) The median initial tidal volume was 6 5 [5 8-7 0] mL/kg predicted body weight and the median initial positive end-expiratory pressure (PEEP) was 12 [12-14] cm H2O Neither value changed during the first 3 days Thirty-three patients (82%) had a plateau pressure 40 mL/cmH2O was observed in 4 patients (10%) on day 1, 3 patients (7%) on day 2, and 5 patients (12%) on day 3 The median PaO2/FiO2 in the 15 patients treated with high-flow nasal cannula (HFNC)/non-invasive ventilation (NIV) and did not require MV was 89 [54-156] mmHg at ICU admission Also, in these patients, the mean respiratory rate was 37 +/- 7 breath/min at ICU admission As of June 20, 2020, 43 patients were alive (mortality rate: 22%);among them, 34 (79%) were discharged from the hospital The majority of patients were younger males;a large proportion had typical ARDS and received MV