Catecholamine content of cochlear and facial nerves. High-performance liquid chromatography analyses in normal and mutant mice.

The catecholamine content in cochlear and facial nerves was determined using high-performance liquid chromatography coupled with electrochemical detection. Minute amounts of norepinephrine were detected in both nerves in normal CBA/ CBA mice and homozygotic jerker mouse mutants, whereas norepinephrine was found only in the facial nerve in the dancer heterozygotic mouse mutant. Dopamine and epinephrine were not detected in any of the mouse strains.