Sertoli’s Cell Tumor, Ovary, Rat

Ovarian Sertoli’s cell tumors are usually unilateral, ranging from 0.2 to 5 cm in diameter (Fig. 29), and weigh from 2 to 40 g. They are most often solid, encapsulated, lobulated, white-yellow masses with occasional cysts filled with clear or blood-tinged fluid (Stoica et al. 1985). Metastases have been detected in 6% of the rats with Sertoli’s cell tumors of the ovary. They appear as multiple miliary nodules disseminated throughout the peritoneal surfaces. The opposite ovary is often smaller than normal in rats with unilateral tumors.