Pilot study on biocompatibility of fluorescent nanodiamond-(NV)-Z~800 particles in rats: safety, pharmacokinetics, and bio-distribution (part III)

Frank C. Barone,Cezary Marcinkiewicz,Jie Li,Mark Sternberg,Peter I. Lelkes,Dmitriy A. Dikin,Peter J. Bergold,Jonathan A. Gerstenhaber,Giora Z. Feuerstein

Pilot study on biocompatibility of fluorescent nanodiamond-(NV)-Z~800 particles in rats: safety, pharmacokinetics, and bio-distribution (part III)

2018

Frank C. Barone
Cezary Marcinkiewicz
Jie Li
Mark Sternberg
Peter I. Lelkes
Dmitriy A. Dikin
Peter J. Bergold
Jonathan A. Gerstenhaber
Giora Z. Feuerstein

Introduction We hereby report on studies aimed to characterize safety, pharmacokinetics, and bio-distribution of fluorescent nanodiamond particles (NV)-Z~800 (FNDP-(NV)) administered to rats by intravenous infusion in a single high dose.

Keywords:

Biocompatibility
Molecular biology
Medicinal chemistry
Materials science
Fluorescence
Nanodiamond
Pharmacokinetics
Preclinical imaging
Hematology
Spleen
Internal medicine
Kidney
Blood cell
Pharmacology
Particle size
Lung

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