Gefitinib reduces the production of osteoclast differentiation factors in human bone marrow stromal cells: Implications for treatment of bone metastasis

N. Normanno,A. De Luca,Donatella Aldinucci,Monica R. Maiello,Mario Mancino,Antonio DAntonio,R. De Filippi,Antonello Pinto

Gefitinib reduces the production of osteoclast differentiation factors in human bone marrow stromal cells: Implications for treatment of bone metastasis

2005

N. Normanno
A. De Luca
Donatella Aldinucci
Monica R. Maiello
Mario Mancino
Antonio DAntonio
R. De Filippi
Antonello Pinto

3119 Background: Clinical studies of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) as monotherapy in breast cancer patients have shown some evidence of activity. Significa...

Keywords:

Bone metastasis
Pathology
Bone marrow
Stromal cell
Osteoclast
Cancer research
Gefitinib
Medicine
human bone
epidermal growth factor receptor tyrosine kinase
Breast cancer

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