Post Transplant Human Cytomegalovirus Infection Can Provoke Acute Kidney Allograft Rejection

Human Cytomegalovirus (HCMV) infection can trigger immunological cascades leading to kidney allograft rejection. In this study we have selected 17 post renal transplant patients with negative Luminex Donor Specific Antibody (DSA) crossmatch and Complement Dependent Cytotoxicity (CDC) crossmatch with Anti Human Globulin (AHG) augmentation. All the 17 patients were detected with post transplant HCMV infection. 4 of the 17 patients were recognized with rejection symptoms identified histologically and among them 1 patient died. The patient who died was co- infected with blood stream Staphylococcus aureus.