IN- VITRO EVALUATION OF ANTHELMINTIC ACTIVITY OF LASIA SPINOSA LEAVES

The present study was aimed to evaluate anthelmintic activity of methanolic extract of leaves of Lasia spinosa against Pheritima posthuma . Three different concentrations (25 mg/ml, 50 mg/ml and 100 mg/ml) of extracts were studied in this activity which involved determination of time of paralysis and time of death of worms. The results of present study indicated that methanolic extract significantly exhibited paralysis and also caused death of worms especially at highest concentration of 100 mg/ml, as compared to standard reference Albendazole (10 mg/ml). Our study found that the leaves of Lasia spinosa possess potent anthelmintic activity.