Iodomethylethers from 1,3-dioxolane and 1,3-oxathiolane: preparation of acyclic nucleoside analogs

Gene E. Keyser,Jerry D. Bryant,Jorge R. Barrio

Iodomethylethers from 1,3-dioxolane and 1,3-oxathiolane: preparation of acyclic nucleoside analogs

1979

Gene E. Keyser
Jerry D. Bryant
Jorge R. Barrio

Abstract Purine and pyrimidine anions were alkylated using the iodomethyl ether and thioether generated in situ by the reaction of 1,3-dioxolane and 1,3-oxathiolane with trimethylsilyl iodide.

Keywords:

Alkylation
Pyrimidine
Ether
Dioxolane
Nucleoside Analogs
Photochemistry
Purine
Trimethylsilyl iodide
Thioether
Organic chemistry
Chemistry
acyclic nucleoside

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