Assessment of autonomic nervous system by spectral analysis of heart rate and blood pressure in hemodialysed patients

The aim of the presented study was to assess autonomic nervous system (ANS) among hemodialysed patients. Twenty-seven pts. were included to the study (15 M, 12 F) and as a control group 22 (12 M, 10 F) healthy persons were taken. To asses cardiovascular part of ANS we used Ewing battery, time and spectral analysis of heart rate variability (HRV) and spectral analysis of blood pressure variability (BPV). QT interval was analyzed from standard 12-lead ECG. The hemodialysed patients showed certain signs of autonomic dysregulation. Forty two percent of pts had abnormalities in Ewing tests most prevalent in parasympathetic part of ANS. Spectral HRV parameters were pathological in 44.4% patients. The low frequency component of BPV was significantly lower in HD patients without changes in the high frequency component. QT interval dispersion and corrected by heart rate QT interval dispersion were significantly higher in hemodialysed patients than in the control group.