Implications of tumor oxygenation and blood flow for cancer treatment monitoring using photoacoustic imaging and power Doppler

Photoacoustic (PA) imaging has been proposed for cancer treatment monitoring. Tumor oxygen saturation (sO 2 ) should in principle be related to vascular parameters such as blood flow. In this work, in-vivo PA estimates of sO 2 were compared to power Doppler (pD) measures of vascularity hours after the administration of microbubbles (MB), radiation therapy (XRT), individually or combined (MB-XRT).