Androgens enhance the glycolytic metabolism and lactate export in prostate cancer cells by modulating the expression of GLUT1, GLUT3, PFK, LDH and MCT4 genes

Cátia V. Vaz,Ricardo Marques,Marco G. Alves,Pedro Oliveira,José E. Cavaco,Cláudio J. Maia,Sílvia Socorro

Androgens enhance the glycolytic metabolism and lactate export in prostate cancer cells by modulating the expression of GLUT1, GLUT3, PFK, LDH and MCT4 genes

2016

Cátia V. Vaz
Ricardo Marques
Marco G. Alves
Pedro Oliveira
José E. Cavaco
Cláudio J. Maia
Sílvia Socorro

Purpose The present study aims to investigate the role of androgens in controlling the glycolytic metabolism and lactate efflux in prostate cancer (PCa) cells.

Keywords:

Metabolism
GLUT1
Prostate cancer
Glycolysis
Endocrinology
Efflux
LNCaP
Phosphofructokinase
GLUT3
Biology
Internal medicine
Biochemistry
Immunology
Cancer research

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