Çocuklarda Henoch-Schönlein Purpurası: 2 Yıllık Tek Merkez Deneyimi

Amac: Henoch-Schonlein purpurasi (HSP) tanisi ile izlenen hastalarin demografik, klinik ve laboratuvar ozelliklerini degerlendirmek ve bobrek tutulumu riski acisindan karsilastirmak Materyal ve metod: Ocak 2015-Ocak 2017 tarihleri arasinda hastanemiz cocuk nefroloji-romatoloji polikliniginde HSP tanisi konup en az 1 yil sure ile izlenen hastalarin dosyalari gozden gecirildi. Demografik veriler, oyku, tani yasi, fizik muayene, laboratuvar tetkikleri, organ tutulumlari, bobrek biyopsileri, tum tedavi rejimleri ve izlemleri degerlendirildi. Bulgular: Calismamizda 2 yillik sure icinde 57’si erkek (% 48.3) 61’i kiz (% 51.7) toplam 118 hasta vardi. Hastalarin yas ortalamasi 7.9 ± 2.81, kiz: erkek orani 1: 0.93 idi. 10 yas altinda 98 hasta (% 83.1) varken, 10 yas uzeri hasta sayisi 20 (% 16.9) idi. Hastalarda yas, cinsiyet, hastalik tekrari, eklem tutulumu yeri ve suresi, dokuntunun yeri ve suresi, gastrointestinal tutulum, testis tutulumu, laboratuar parametreleri ile bobrek tutulumu karsilastirildiginda anlamli bir iliski saptanmadi. Sonuc: Iki yillik sure icinde HSP tanisi ile izledigimiz hastalari geriye donuk olarak degerlendirdigimizde bobrek tutulumu acisindan risk faktorlerine baktigimizda anlamli bir faktor tespit edemedik. Aslinda bu durum bize tum HSP hastalarinin dikkatli bir bicimde renal tutulum acisindan takip edilmesi gerektigini dusundurmektedir. Abstract Background: To evaluate the demographic, clinical and laboratory characteristics of patients with Henoch-Schonlein purpura (HSP) and compare the risk of renal involvement Materials and Methods: The files of the patients who were diagnosed as HSP in the pediatric nephrology-rheumatology clinic of our hospital between January 2015 and January 2017 and followed for at least 1 year were reviewed. Demographic data, history, age at diagnosis, physical examination, laboratory tests, organ involvement, renal biopsies, all treatment regimens and follow-up were evaluated. Results: There were 118 patients 57 male (48.3%), 61 female (51.7%) in a 2-year period. The mean age of the patients was 7.9 ± 2.81 and the female: male ratio was 1: 0.93. While there were 98 patients (83.1%) under 10 years of age, the number of patients over 10 years of age was 20 (16.9%). There was no significant relationship between age, sex, recurrence of disease, location and duration of joint involvement, location and duration of rash, gastrointestinal involvement, testicular involvement, laboratory parameters and renal involvement. Conclusion: When we retrospectively evaluated the patients whom were followed up with the diagnosis of HSP over a two-year period, we did not find any significant factor in the risk factors for renal involvement. In fact, this suggests that all HSP patients should be carefully monitored for renal involvement.