RENAL ANJİOMYOLİPOMLAR: 15 OLGUNUN ANALİZİ

Purpose: Angiomyolipoma (AML) is a benign mesenchymal tumor in which mature adipose tissue, thick walled vasculature, smooth muscle tissue and special myoid cells expressing melanin are observed in varying proportions. In this article, we aimed to present the patients with different clinical and microscopic features diagnosed with renal AML in our clinic between 2008-2018 and provide acurrent information in the diagnosis of AML. Material and Methods: Fifteen Renal AML cases which were diagnosed Department of Medical Pathology between 2008-2018 were retrospectively evaluated. Results: Two of the 15 patients were male and 13 were female and their ages ranged from 37 to 74 years (mean59±10 years). Their sizes were between 0.7 and 15 cm and averaged 5.1±3,2 cm. One patient had tuberous sclerosis. In 7 cases, capsule integrity was lost and in one case perforation was observed. Microscopic examination revealed mature adipose tissue, thick walled vein structures and spindle epithelioid cells in 13 cases. Four cases were rich in adipose tissue, 1 case was rich in spindle epithelioid cells and 3 cases were rich in vascular structures. Conclusion: AML is a tumour which is characterized by different clinical features, microscopic and macroscopic findings. It can be observed incidentally, and can be detected by complications such as bleeding and perforation when it reaches a very large size. It is important to keep in mind in differential diagnosis that not all components can always coexist and that certain components can be dominant. Key words: Angiomyolipoma, tuberoussclerosis, kidney