[Molecular-epidemiological characteristics of HIV-1 isolated from newly diagnosed female subjects in Beijing, 2006 - 2010].

Objective To analyze the molecular-epidemiological characteristics of HIV-1 strains prevailing among female people living with HIV in Beijing.Methods Gag gene fragments from the 100 newly diagnosed female HIV-1 infections during 2006 to 2010 in Beijing were amplified,sequenced,and phylogenetically analyzed.Results Eighty-two HIV-1 gag gene fragments were amplified and analyzed.1 (1.22％),1 (1.22％),3(3.66％),23(28.05％),8(9.76％),2(2.44％),1 (1.22％),18 (21.95％),3 (3.66％),1 (1.22％),14 (17.07％),4 (4.88％) and 3 (3.66％) individuals were infected with HIV-1 subtypes A 1,A2,B,B',C,D,G,H,CRF0 1_AE,CRF02_AG,CRF07_BC,CRF08_BC and B'/C recombinants respectively.Conclusion The subtypes circulating in females HIV infections in Beijing were more diversities than in males and the proportions of B' and rare subtypes were relatively high.Surveillance programs on HIV-1 genetic diversity should be strengthened. Key words: Human immunodeficiency virus; Subtype; Nested-PCR