P321: Survival of malnourished elderly patients receiving post-adischarge nutritional support; a randomized controlled study

SURVIVAL OF MALNOURISHED ELDERLY PATIENTS RECEIVING POST-DISCHARGE NUTRITIONAL SUPPORT; A RANDOMIZED CONTROLLED STUDY Floor Neelemaat* 1, Suzanne van Keeken2, Jacqueline Langius1, Marian de van der Schueren1, Abel Thijs3, Judith Bosmans4 1Nutrition and Dietetics / Internal Medicine, VU University Medical Center, 2Nutrition and Health, VU University, 3Internal Medicine, VU University Medical Center, 4Health Sciences, VU University, Amsterdam, Netherlands Rationale: In malnourished elderly patients, a post-discharge individualized nutritional intervention has shown to have positive effects on body weight, lean body mass, fall incidents and functional limitations1,2. However, the impact on survival is still unclear. Therefore, the aim of this randomized controlled study was to examine the effect of this nutritional intervention on survival in malnourished elderly patients. Methods: 210 malnourished elderly patients, aged ≥60 years, were randomized during hospitalization to a 3months post-discharge nutritional intervention group (protein and energy enriched diet, oral nutritional supplements, vitamin D3/calcium supplement and dietetic telephone counseling) or to a control group (usual care regimen). Survival data was evaluated 1 year and 4 years post-discharge. Survival analyses were performed using intention-to-treat analysis by Cox regression. Results: The study population consisted of 94 men (45%) and 116 women with a mean age of 74.5 (SD 9.5) years. Baseline characteristics were not different between groups. There were no statistically significant differences in survival between groups (Table 1). Table 1: Survival rates at 1 and 4 years following 3-months post-discharge nutritional intervention in malnourished elderly patients