Age-Related Cataract and Serum Albumin Concentration

Purpose: Searching for new factors which might be important in age-related cataractogenesis. A possible association between serum albumin concentration and age-related cataract has already been recognized, but their relationship is not quite apparent. Materials and Methods: Retrospective cross-section study on 157 age-related cataract patients and 55 age- and sex-matched control subjects. Blood for analyses was taken under the same conditions in all individuals. Serum albumin concentration was measured by a colorimetric method. Findings were interpreted according to their age, and in cataract patients, related to the main opacities found. Statistical data were obtained by t-test, Spearman's rank coefficient correlation, and ANOVA. Results: A significant difference between measured serum albumin in the cataract and control group has not been found. In cataract patients, serum albumin concentration was significantly negatively associated with their age (65 and onward, compared to younger cataract patients) ...