Cognitive Performance, Aerobic Fitness, Motor Proficiency, and Brain Function Among Children Newly Diagnosed With Craniopharyngioma

OBJECTIVES: Craniopharyngioma survivors experience cognitive deficits that negatively impact quality of life. Aerobic fitness is associated with cognitive benefits in typically developing children and physical exercise promotes recovery following brain injury. Accordingly, we investigated cognitive and neural correlates of aerobic fitness in a sample of craniopharyngioma patients. METHODS: Patients treated for craniopharyngioma [N=104, 10.0±4.6 years, 48% male] participated in fitness, cognitive and fMRI (n=51) assessments following surgery but before proton radiation therapy. RESULTS: Patients demonstrated impaired aerobic fitness [peak oxygen uptake (PKVO2)=23.9±7.1, 41% impaired (i.e., 1.5 SD

Keywords:

• Developmental psychology
• Craniopharyngioma
• Psychology
• Effects of sleep deprivation on cognitive performance
• Aerobic exercise
• Physical exercise
• Cognition
• Acquired brain injury
• Working memory
• Executive functions
• Audiology
• Dorsolateral prefrontal cortex

• Correction
• Source
• Cite
• Save
• Machine Reading By IdeaReader