EFEKTIVITAS EKSTRAK ETANOL DAN AIR DAUN DURIAN (Durio zibethinus Murr) TERHADAP LARVAAnopheles aconitus DONITZ DAN Anopheles maculatus THEOBALD (DIPTERA : CULICIDAE)

Anopheles aconitus Donitz and Anopheles maculatus Theobald are examples of the dominant vectors of malaria insect in Indonesia. The use of chemicals in controlling malaria vectors cause some worse effects such as the emergence of resistance. Plants have variety of secondary metabolites that can be used as more secure alternative to substitute the chemicals. Durian (Durio zibethinus Murr) leaf supposed of having active compounds that can be used as botanical larvicide to kill mosquito larvae. This research aims to evaluate efficacy of botanical larvicide D. zibethinus leaf extracts against An. aconitus and An. maculatus larvae and determinate concentration, extract type, and secondary metabolite compounds of D. zibethinus leaf extracts. Leaves extraction done by maceration for ethanol solvent and remaceration for aqueous solvent. Phytochemical screening conducted to determine the active compounds in D. zibethinus leaves. Larvicides test based on insecticide bioassay test procedures from WHO. Concentrations of ethanol extract were 200