Mesenchymal stem cell exosomes as a cell-free therapy for nerve injury–induced pain in rats

AbstractNerve injury–induced neuropathic pain is difficult to treat. In this study, we used exosomes derived from human umbilical cord mesenchymal stem cell (UCMSC) as a cell-free therapy for nerve injury–induced pain in rats. Isolated UCMSC exosomes range in size from 30 to 160 nm and contain CD63,