The Two-Minutes-Flow-Index (TMFI)

While performing clinical rCBF functional tests it is difficult to maintain the patient in a stationary condition over the entire clearance period. For this reason it has become a common practice to restrict the recording of the clearance curves to the first 2 min [1, 2, 3]. This gives rise to one question: 1. Is it possible to evaluate the information contained in these 2 min of the clearance curve so as to obtain a quantifiable measure for rCBF?