IN VIVO CANCER DIAGNOSTICS BY SPACE RESOLVED DIFFUSE REFLECTANCE SPECTROSCOPY

In this paper we describe a compact, portable light-emitting diode (LED)-based fiber-optic system allowing in vivo diffuse reflectance spectra registration in visible and near IR spectral range at two distances between illuminating and collecting fibers. The construction of fiber optic probe is adapted for endoscopy application. We further report the preliminary results of in vivo discrimination between of the benign and malignant tissues and different types of malignant tissues in the animal models.