Transcriptomic analysis of skin in a case of ichthyosis Curth–Macklin caused by a KRT1 mutation

Ichthyosis Curth–Macklin (ICM) can be considered one of the most drastic forms of genetically-derived keratin disease. Individuals suffering from ICM mainly display severe palmoplantar keratoderma and dark spiky plaques which may affect the entire body. This article is protected by copyright. All rights reserved.