Opioid-Induced Hyperalgesia in the Nonsurgical Setting: A Systematic Review
2018
Background:Opioid-induced hyperalgesia (OIH) is a phenomenon that causes an increased pain sensitization and perception of pain to noxious stimuli secondary to opioid exposure. While this clinical effect has been described in the surgical setting, it is unclear if OIH occurs in the nonsurgical setti
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