Low dose spiral CT combined with selective use of PET scans can detect early lung cancer

▴ Pastorino U, Bellomi M, Landoni C, et al . Early lung-cancer detection with spiral CT and positron emission tomography in heavy smokers: 2 year results. Lancet2003;362:593–7 [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] This non-randomised study of 1035 smokers (⩾20 pack years) evaluated screening using positron emission tomography (PET) in addition to spiral computed tomography (CT) to improve assessment of lesions. All patients had baseline CT and annual scans for 5 years. Calcified nodular lesions or non-calcified nodules (NCN) <5 mm were deemed … [1]: {openurl}?query=rft.jtitle%253DLancet%26rft.stitle%253DLancet%26rft.aulast%253DPastorino%26rft.auinit1%253DU.%26rft.volume%253D362%26rft.issue%253D9384%26rft.spage%253D593%26rft.epage%253D597%26rft.atitle%253DEarly%2Blung-cancer%2Bdetection%2Bwith%2Bspiral%2BCT%2Band%2Bpositron%2Bemission%2Btomography%2Bin%2Bheavy%2Bsmokers%253A%2B2-year%2Bresults.%26rft_id%253Dinfo%253Adoi%252F10.1016%252FS0140-6736%252803%252914188-8%26rft_id%253Dinfo%253Apmid%252F12944057%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1016/S0140-6736(03)14188-8&link_type=DOI [3]: /lookup/external-ref?access_num=12944057&link_type=MED&atom=%2Fthoraxjnl%2F58%2F12%2F1082.atom [4]: /lookup/external-ref?access_num=000184904100006&link_type=ISI