Early and late results of total correction of congenital cardiac anomalies in infancy

Objective: We evaluated long-term results of surgical correction of congenital cardiac anomalies in infancy.Methods: We reviewed cases of 856 patients who underwent complete correction of major cardiac anomalies in the first year of life during last 24 years at our institution, and analyzed results. Surgery involved ventricular septal defect (n=453), tetralogy of Fallot (n=92), atrioventricular canal defect (n=93), and complete transposition of the great arteries (n=218).Results: Operative mortality was 2.2% in ventricular septal defect, 0% in tetralogy of Fallot, 8.6% in atrioventricular canal defect, and 4.1% in complete transposition of the great arteries. Freedom from reoperation at 20 years was 96.5±2.0% and actuarial survival was 94.2±1.3% in ventricular septal defect. Freedom from reoperation at 15 years was 90.5±3.9% in tetralogy of Fallot and 86.6±4.4% in atrioventricular canal defect. Actuarial survival at 15 years was 97.8±1.6% in tetralogy of Fallot, 85.7±3.7% in atrioventricular canal defect, and 89.9±2.2% in complete transposition of the great arteries. Actuarial survival in complete transposition of the great arteries was significantly better in arterial than in atrial switch operations.Conclusions: Total correction of ventricular septal defect, tetralogy of Fallot, atrioventricular canal defect, and complete transposition of the great arteries in infancy was conducted safely, but the incidence of reoperation in late follow-up must be reduced.