Primary Cutaneous Gamma-delta T-cell Lymphoma: Predominant Subcutaneous Uptake Detected by 18 F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomographic Scan in a Rapidly Deteriorating Patient

Primary cutaneous gamma-delta T-cell lymphoma is a rare subtype of primary cutaneous peripheral T-cell lymphoma. In the latest World Health Organization / European Organisation for Research and Treatment of Cancer classification and World Health Organization classification (4th edition, 2008), the entity previously called “subcutaneous panniculitis-like T-cell lymphoma with gamma-delta T-cell phenotype” has been reclassified as a form of primary cutaneous gamma-delta T-cell lymphoma. Most literature reported low positive rates of 18 F-fluorodeoxyglucose positron emission tomography/computed tomographic scans in patients with cutaneous lesions. To our knowledge, the pattern of diffuse predominant subcutaneous uptake in cutaneous gamma-delta T-cell lymphoma using positron emission tomography/computed tomographic scans has rarely been described. In this report, we describe the clinical presentation, pathological findings, and the predominant subcutaneous uptake pattern revealed by positron emission tomography/computed tomographic scanning in a patient with a subcutaneous fat biopsy proven peripheral T-cell lymphoma of the gamma-delta phenotype.