R2* Relaxometry in Sclerotic Hippocampi of Patients with Temporal Lobe Epilepsy

Pharmacoresistance to antiepileptic therapy is a frequently observed phenomenon in mesial temporal lobe epilepsy with hippocampal sclerosis (HS-TLE). Neurosurgical intervention can be an alternative treatment in drug- resistant HS-TLE patients. Several studies have already proven that in unilateral MRI abnormality, which is most frequently hippocampal sclerosis, predicts a more favorable seizure outcome.