Intracranial Pressure Changes during Experimental Cerebral Infarction

The role of intracranial pressure gradients in the development of neurologic deficits after cerebral infarction has not been evaluated adequately, partly because of technical problems with measurements of regional intracranial pressure (ICP). The presumed cause of post-infarction ICP gradients is ischemic cerebral edema; as a preliminary to a study of edema and its modification by treatment, ICP was measured in cats after occlusion of one middle cerebral artery (MCA).