Osteopoikilosis Associated With Both Ichthyosis Vulgaris And Crohn's Disease
1985
We report a rare case of Osteopoikilosis associated with ichthyosis vulgaris and Crohn's disease. A 26-year-old man who was told of an “abnormal” radiograph was referred to our department. A skeletal survey was performed which revealed multiple oval and round densities measuring 3-7mm in diameter. The lesions were bilaterally situated in the epiphysio-metaphyseal region. The bones involved were the long bones and the small bones of the hands, feet, and pelvis. The ribs, skull and vertebral column were not involved. 99mTc-methylen diphosphate bone scan was performed and found to be normal. We describe here a case with osteopoikilosis, Crohn's disease and ichthyosis vulgaris. The etiology of the conditions was unknown, but we subsequently turned our attention to a possible link among these three conditions. The combination of osteopoikilosis, ichthyosis vulgaris, and Crohn's disease is considered a syndrome which is possibly inherited.
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