N-of-1- pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes

Qike Li,A. Grant Schissler,Vincent Gardeux,Ikbel Achour,Colleen Kenost,Joanne Berghout,Haiquan Li,Hao Helen Zhang,Yves A. Lussier

N-of-1- pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes

2017

Qike Li
A. Grant Schissler
Vincent Gardeux
Ikbel Achour
Colleen Kenost
Joanne Berghout
Haiquan Li
Hao Helen Zhang
Yves A. Lussier

NIH [K22LM008308]; NSF [DMS-1309507, DMS-1418172]; University of Arizona Center for Biomedical Informatics and Biostatistics; NCI of the University of Arizona Cancer Center [P30CA023074]

Keywords:

Bioinformatics
Precision medicine
Gene expression
Genetics
Biostatistics
RNA-Seq
Human genetics
Transcriptome
Biology
Health informatics
Wilcoxon signed-rank test
Mahalanobis distance
DNA microarray
Receiver operating characteristic

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