[19-OR]: Evaluation of fetal renal vascularization in pregnancies complicated by essential and pregnancy induced hypertension

Objectives Our goal was to establish fetal renal vascularization in pregnancies complicated by essential and pregnancy induced hypertension by 3-dimensional sonography using VOCAL (Virtual Organ Computer-Aided Analysis) method. Methods 52 pregnant women who were examined between 20 and 38 weeks of their pregnancies complicated by essential ( N  = 30) and pregnancy induced hypertension ( N  = 22) were involved in this prospective longitudinal study. During the examination fetal kidneys were evaluated separately using VOCAL method with a 3-dimensional power Doppler technique. The following measurements were taken in connection with the right and left kidneys: vascularization index, flow index, vascularization flow index. Wilcoxon rank-sum test was carried out to assess the relationship between fetal renal vascularization in pregnancies complicated by essential as well as pregnancy induced hypertension. Student’s t -test was performed to evaluate the concordance between the fetal renal vascularization in normal and complicated cases. Results The mean values of fetal renal vascularization decreased in complicated cases, but significant difference ( p p p Conclusions Fetal renal vascularization (vascularization index, flow index and vascularization flow index) were significantly depressed in case of maternal hypertension. Fetal downregulated vascularization had influence on fetal renal development. Fetal renal 3-dimensional power Doppler investigations show potential correlation between vascular indices and postnatal renal function. Disclosures A. Suranyi: None. A. Altorjay: None. T. Nyari: None. A. Pal: None.