NON-RECOMMENDED DOSING OF DIRECT ORAL ANTICOAGULANTS IN THE TREATMENT OF ACUTE PULMONARY EMBOLISM IS RELATED TO AN INCREASED RATE OF ADVERSE EVENTS

Dose adjustment of direct oral anticoagulants (DOACs) is not required in the setting of acute PE treatment other than the contraindication in severe renal insufficiency. Prospective, multicenter cohort study to investigate the risk associated with prescription of non-recommended DOAC doses. The