Investigation of the antagonistic activity of spore probiotics against Rhodococcus equi in experiments on mice

A method is developed for studying the antagonistic activity of the spore probiotics Sakhabactisubtil and Irilis in vivo against a virulent Rhodococcus equi. Intraperitoneal injection of sterile filtrates of these spore probiotics into mice that received the antibiotic Ampiox and were infected with a lethal dose of the virulent R. equi strain promotes the survival of 70–100% of the animals and reduced the number of rhodococci in internal organs by 6–9 times.