Pharmacoeconomics comparison of application of antibiotics in acute appendicitis clinical pathway.

OBJECTIVE:To probe into the treatment efficacy and pharmacoeconomics comparison of application of antibiotics in acute appendicitis clinical pathway.METHODS:288 cases of acute appendicitis clinical pathway discharged from People's Hospital of Nanjing Gaochun from Jan.2012 to Dec.2013 were selected to analyze the application of antibiotics.The costs like hospitalization costs,drug costs and antibiotics costs were statistically analyzed.RESULTS:The scheme of β-lactams were mainly used in simple appendicitis,the hospitalization and antibiotics costs in patients treated with cefoxitin were lower than those with cefotiam.The scheme of β-lactams combined with nitrodazoles were mainly used in suppurative appendicitis,hospitalization and antibiotics costs in patients treated with cefotiam combined with metronidazole were lower than those of other schemes.CONCLUSIONS:The application of cefoxitin in simple appendicitis,the application of cefotiam combined with metronidazole insuppurative,gangrenous and perforated appendicitis both have the pharmacoeconomics advantages.